The study published in the journal for Cancer Research states that scientists have developed a new technique in which they use a genetically modified virus for killing cancer cells and even has the ability to destroy their hiding places. Named as the enadenotucirev, this novel dual action virus targets cancer cells as well as the healthy cells that are tricked into cancer cell protection by the immune system of the body called fibro-blasts.
The therapy used presently for killing the tricked viruses of cancer may also kill the fibroblast cells leading to toxicity. Carcinomas, the most common kind of cancer are found to start in the cells of the skin or in the tissues covering or lining internal organs like lungs, pancreas, breasts, colon, prostate and ovaries.
As per Kerry Fisher of Britain’s University of Oxford there hasn’t been any way where you can kill the cancer cells and the fibroblasts that are known to protect them as well, without causing any harm to the other parts of the body. Therefore, this technique that can be used for targeting the cancer cells as well as the fibroblasts is definitely cited as a vital development in reducing the suppression inside the carcinomas as well as initiating the normal immune process.
The team included some genetic instructions before publishing the study in the journal order the infected cancer cells to produce a protein called bispecific T cell engager, that has the ability to bind and stick two cells together. Here the first end is fibroblasts and the second end is T cells – a kind of immune cell that kills defective cells. The result, T cells started killing attached fibroblasts. The team also carried out the testing of the virus on a human bone marrow successfully to find that the process did not result in creating any toxicity to the rest of the body or any inappropriate activation of T cells.
The clinical trials of Enadenotucirev have already started for carcinoma treatment and in the upcoming year it will begin its clinical trials of finding out the safety and affectivity of it on people suffering from cancer.
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*Sourced from the Internet